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IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis
BACKGROUND: Vascular endothelial growth factor receptor-2 (VEGFR-2) signaling is an obligate requirement for normal development and pathological angiogenesis such as cancer and age-related macular degeneration. Although autophosphorylation of tyrosine 1173 (Y1173) of VEGFR-2 is considered a focal po...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585478/ https://www.ncbi.nlm.nih.gov/pubmed/19050761 http://dx.doi.org/10.1371/journal.pone.0003848 |