Cargando…
IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis
BACKGROUND: Vascular endothelial growth factor receptor-2 (VEGFR-2) signaling is an obligate requirement for normal development and pathological angiogenesis such as cancer and age-related macular degeneration. Although autophosphorylation of tyrosine 1173 (Y1173) of VEGFR-2 is considered a focal po...
Autores principales: | Meyer, Rosana D., Sacks, David B., Rahimi, Nader |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585478/ https://www.ncbi.nlm.nih.gov/pubmed/19050761 http://dx.doi.org/10.1371/journal.pone.0003848 |
Ejemplares similares
-
Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis
por: Sullivan, David P., et al.
Publicado: (2019) -
Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras
por: Morgan, Chase J., et al.
Publicado: (2019) -
IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
por: White, Colin D, et al.
Publicado: (2010) -
IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway
por: Quinn, Niall P., et al.
Publicado: (2021) -
IQGAP1 Is a Phosphotyrosine-Regulated Scaffold for SH2-Containing Proteins
por: Thines, Louise, et al.
Publicado: (2023)