Cargando…

Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors

BACKGROUND: A recent study has shown that phosphorylated c-Jun (p-c-Jun) interacts with TCF4 to form a complex that cooperatively enhances their transcriptional activity in the presence of β-Catenin, and that their interaction is critical for mouse intestinal tumorigenesis. To determine the signific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takeda, Kayoko, Kinoshita, Ichiro, Shimizu, Yasushi, Ohba, Yusuke, Itoh, Tomoo, Matsuno, Yoshihiro, Shichinohe, Toshiaki, Dosaka-Akita, Hirotoshi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585585/ https://www.ncbi.nlm.nih.gov/pubmed/18992165 http://dx.doi.org/10.1186/1471-2407-8-328

Ejemplares similares

A Case of High-Grade Neuroendocrine Carcinoma That Improved with Bevacizumab plus Modified FOLFOX6 as the Fourth-Line Chemotherapy
por: Takeuchi, Satoshi, et al.
Publicado: (2011)

Crystalline silica-exposed human lung epithelial cells presented enhanced anchorage-independent growth with upregulated expression of BRD4 and EZH2 in autocrine and paracrine manners
por: Katabami, Motoo, et al.
Publicado: (2023)

Role of targeted therapy in metastatic colorectal cancer
por: Ohhara, Yoshihito, et al.
Publicado: (2016)

Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
por: Gan, Xiao-qing, et al.
Publicado: (2008)

Down-regulation of Human Leukocyte Antigen class I heavy chain in tumors is associated with a poor prognosis in advanced esophageal cancer patients
por: TANAKA, KIMITAKA, et al.
Publicado: (2011)

Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non‐small‐cell lung cancer cells
por: Takashina, Taichi, et al.
Publicado: (2016)

Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant
por: Shimizu, Y, et al.
Publicado: (2008)

EGFR inhibition in EGFR‐mutant lung cancer cells perturbs innate immune signaling pathways in the tumor microenvironment
por: Shiiya, Akihiko, et al.
Publicado: (2022)

Expression of Karyopherin Alpha 2 and Karyopherin Beta 1 Correlate with Poor Prognosis in Gastric Cancer
por: Ohhara, Yoshihito, et al.
Publicado: (2022)

Autophagy-dependent regulation of tumor metastasis by myeloid cells
por: Jinushi, Masahisa, et al.
Publicado: (2017)

Expression of Bim, Noxa, and Puma in non-small cell lung cancer
por: Sakakibara-Konishi, Jun, et al.
Publicado: (2012)

Roles of β-catenin, TCF-4, and survivin in nasopharyngeal carcinoma: correlation with clinicopathological features and prognostic significance
por: Jin, Pei-Ying, et al.
Publicado: (2019)

Biomarker testing for personalized, first-line therapy in advanced nonsquamous non-small cell lung cancer patients in the real world setting in Japan: a retrospective, multicenter, observational study (the BRAVE study)
por: Shimizu, Junichi, et al.
Publicado: (2020)

Tcf3 Represses Wnt–β-Catenin Signaling and Maintains Neural Stem Cell Population during Neocortical Development
por: Kuwahara, Atsushi, et al.
Publicado: (2014)

DLL3 regulates the migration and invasion of small cell lung cancer by modulating Snail
por: Furuta, Megumi, et al.
Publicado: (2019)

Early prediction of lenvatinib treatment efficacy by using (18)F-FDG PET/CT in patients with unresectable or advanced thyroid carcinoma that is refractory to radioiodine treatment: a protocol for a non-randomized single-arm multicenter observational study
por: Takeuchi, Satoshi, et al.
Publicado: (2018)

Survey of the management of chemotherapy-induced peripheral neuropathy in Japan: Japanese Society of Medical Oncology
por: Hirayama, Yasuo, et al.
Publicado: (2016)

Low expression levels of microRNA-124-5p correlated with poor prognosis in colorectal cancer via targeting of SMC4
por: Jinushi, Takafumi, et al.
Publicado: (2014)

Early prediction of treatment outcome for lenvatinib using (18)F-FDG PET/CT in patients with unresectable or advanced thyroid carcinoma refractory to radioiodine treatment: a prospective, multicentre, non-randomised study
por: Takeuchi, Satoshi, et al.
Publicado: (2023)

Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer
por: Elmansuri, Aiman Z., et al.
Publicado: (2016)

Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma
por: Kikuchi, Hajime, et al.
Publicado: (2018)

Clinicopathological Factors Related to Recurrence Patterns of Resected Non-Small Cell Lung Cancer
por: Shimizu, Reiko, et al.
Publicado: (2020)

Suppression of neointima formation by targeting β-catenin/TCF pathway
por: Williams, Helen, et al.
Publicado: (2016)

CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma
por: Fan, Xin, et al.
Publicado: (2016)

Assessment for the timing of comprehensive genomic profiling tests in patients with advanced solid cancers
por: Hagio, Kanako, et al.
Publicado: (2023)

Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells
por: Kikuchi, J, et al.
Publicado: (2008)

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain
por: Wisniewska, Marta B.
Publicado: (2013)

Evolution and loss of ß-catenin and TCF-dependent axis specification in insects
por: Schmidt-Ott, Urs, et al.
Publicado: (2022)

NOP7 interacts with β-catenin and activates β-catenin/TCF signaling in hepatocellular carcinoma cells
por: Wu, Nan, et al.
Publicado: (2018)

Identification of novel serum autoantibodies against EID3 in non-functional pancreatic neuroendocrine tumors
por: Hontani, Koji, et al.
Publicado: (2017)

Clinical impact of a cancer genomic profiling test using an in‐house comprehensive targeted sequencing system
por: Hayashi, Hideyuki, et al.
Publicado: (2020)

A Japanese lung cancer registry study on demographics and treatment modalities in medically treated patients
por: Sekine, Ikuo, et al.
Publicado: (2020)

Isolation and Characterization of Human NBL4, a Gene Involved in the β‐Catenin/Tcf Signaling Pathway
por: Ishiguro, Hideyuki, et al.
Publicado: (2000)

Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer
por: Yokouchi, Hiroshi, et al.
Publicado: (2007)

N-acetylgalactosaminyl transferase-3 is a potential new marker for non-small cell lung cancers
por: Dosaka-Akita, H, et al.
Publicado: (2002)

Physiological regulation of β-catenin stability by Tcf3 and CK1ε
por: Lee, Ethan, et al.
Publicado: (2001)

TCF/β-catenin plays an important role in HCCR-1 oncogene expression
por: Cho, Goang-Won, et al.
Publicado: (2009)

TFCP2 activates beta-catenin/TCF signaling in the progression of pancreatic cancer
por: Yuedi, Dai, et al.
Publicado: (2017)

VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry
por: Delgado-Bellido, Daniel, et al.
Publicado: (2023)

Late Onset of Non-islet Cell Tumor Hypoglycemia Managed via Multidisciplinary Treatment in a Patient with a Solitary Fibrous Tumor
por: Takeuchi, Satoshi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_aaje3t62tpoprn448t2aimk8fv