Cargando…

Targeting the X Chromosome during Spermatogenesis Induces Y Chromosome Transmission Ratio Distortion and Early Dominant Embryo Lethality in Anopheles gambiae

We have exploited the high selectivity of the homing endonuclease I-PpoI for the X-linked Anopheles gambiae 28S ribosomal genes to selectively target X chromosome carrying spermatozoa. Our data demonstrated that in heterozygous males, the expression of I-PpoI in the testes induced a strong bias towa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Windbichler, Nikolai, Papathanos, Philippos Aris, Crisanti, Andrea
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585807/ https://www.ncbi.nlm.nih.gov/pubmed/19057670 http://dx.doi.org/10.1371/journal.pgen.1000291

Ejemplares similares

Demasculinization of the Anopheles gambiae X chromosome
por: Magnusson, Kalle, et al.
Publicado: (2012)

Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos
por: Windbichler, Nikolai, et al.
Publicado: (2007)

Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex
por: Bernardini, Federica, et al.
Publicado: (2017)

The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies
por: Papathanos, Philippos A, et al.
Publicado: (2009)

Transcription Regulation of Sex-Biased Genes during Ontogeny in the Malaria Vector Anopheles gambiae
por: Magnusson, Kalle, et al.
Publicado: (2011)

Redkmer: An Assembly-Free Pipeline for the Identification of Abundant and Specific X-Chromosome Target Sequences for X-Shredding by CRISPR Endonucleases
por: Papathanos, Philippos Aris, et al.
Publicado: (2018)

A CRISPR-Cas9 sex-ratio distortion system for genetic control
por: Galizi, Roberto, et al.
Publicado: (2016)

Engineered sex ratio distortion by X-shredding in the global agricultural pest Ceratitis capitata
por: Meccariello, Angela, et al.
Publicado: (2021)

High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation
por: Taxiarchi, Chrysanthi, et al.
Publicado: (2019)

Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis
por: Bernardini, Federica, et al.
Publicado: (2019)

A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters
por: Fasulo, Barbara, et al.
Publicado: (2020)

Publisher Correction: Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis
por: Bernardini, Federica, et al.
Publicado: (2019)

Detecting the population dynamics of an autosomal sex ratio distorter transgene in malaria vector mosquitoes
por: Pollegioni, Paola, et al.
Publicado: (2020)

Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome
por: Page, Nicole, et al.
Publicado: (2023)

Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes
por: Papa, Francesco, et al.
Publicado: (2017)

Cellular mechanisms regulating synthetic sex ratio distortion in the Anopheles gambiae germline
por: Haghighat-Khah, Roya Elaine, et al.
Publicado: (2020)

Spatial distribution of the chromosomal forms of anopheles gambiae in Mali
por: Sogoba, Nafomon, et al.
Publicado: (2008)

A chromosomal reference genome sequence for the malaria mosquito, Anopheles gambiae, Giles, 1902, Ifakara strain
por: Habtewold, Tibebu, et al.
Publicado: (2023)

The circadian clock modulates Anopheles gambiae infection with Plasmodium falciparum
por: Habtewold, Tibebu, et al.
Publicado: (2022)

Rationally-engineered reproductive barriers using CRISPR & CRISPRa: an evaluation of the synthetic species concept in Drosophila melanogaster
por: Waters, Andrew J., et al.
Publicado: (2018)

Tools for Anopheles gambiae Transgenesis
por: Volohonsky, Gloria, et al.
Publicado: (2015)

Breakpoint structure of the Anopheles gambiae 2Rb chromosomal inversion
por: Lobo, Neil F, et al.
Publicado: (2010)

Structural Variation of the X Chromosome Heterochromatin in the Anopheles gambiae Complex
por: Sharma, Atashi, et al.
Publicado: (2020)

A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae
por: Simoni, Alekos, et al.
Publicado: (2020)

A synthetic sex ratio distortion system for the control of the human malaria mosquito
por: Galizi, Roberto, et al.
Publicado: (2014)

In Silico Karyotyping of Chromosomally Polymorphic Malaria Mosquitoes in the Anopheles gambiae Complex
por: Love, R. Rebecca, et al.
Publicado: (2019)

X chromosome transmission ratio distortion in Cftr +/- intercross-derived mice
por: Haston, Christina K, et al.
Publicado: (2007)

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
por: Windbichler, Nikolai, et al.
Publicado: (2011)

Author Correction: A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae
por: Simoni, Alekos, et al.
Publicado: (2020)

2La chromosomal inversion enhances thermal tolerance of Anopheles gambiae larvae
por: Rocca, Kyle AC, et al.
Publicado: (2009)

Chromosome Inversions, Genomic Differentiation and Speciation in the African Malaria Mosquito Anopheles gambiae
por: Lee, Yoosook, et al.
Publicado: (2013)

A CRISPR-Cas9 Gene Drive System Targeting Female Reproduction in the Malaria Mosquito vector Anopheles gambiae
por: Hammond, Andrew, et al.
Publicado: (2015)

Integral gene drives for population replacement
por: Nash, Alexander, et al.
Publicado: (2018)

Differential Plasmodium falciparum infection of Anopheles gambiae s.s. molecular and chromosomal forms in Mali
por: Fryxell, Rebecca T Trout, et al.
Publicado: (2012)

The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa
por: Riehle, Michelle M, et al.
Publicado: (2017)

Genetic Dissection and Validation of Chromosomal Regions for Transmission Ratio Distortion in Intersubspecific Crosses of Rice
por: Zhang, Chaopu, et al.
Publicado: (2020)

Intronic gRNAs for the Construction of Minimal Gene Drive Systems
por: Nash, Alexander, et al.
Publicado: (2022)

PCR-based karyotyping of Anopheles gambiae inversion 2Rj identifies the BAMAKO chromosomal form
por: Coulibaly, Mamadou B, et al.
Publicado: (2007)

Perfect association between spatial swarm segregation and the X-chromosome speciation island in hybridizing Anopheles coluzzii and Anopheles gambiae populations
por: Niang, Abdoulaye, et al.
Publicado: (2022)

A Novel Sperm-Delivered Toxin Causes Late-Stage Embryo Lethality and Transmission Ratio Distortion in C. elegans
por: Seidel, Hannah S., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_khtv4iq3j63qffkmj557pe18lq