Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

Melanin protects the skin and eyes from the harmful effects of UV irradiation, protects neural cells from toxic insults, and is required for sound conduction in the inner ear. Aberrant regulation of melanogenesis underlies skin disorders (melasma and vitiligo), neurologic disorders (Parkinson's...

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Detalles Bibliográficos
Autores principales: Ganesan, Anand K., Ho, Hsiang, Bodemann, Brian, Petersen, Sean, Aruri, Jayavani, Koshy, Shiney, Richardson, Zachary, Le, Lu Q., Krasieva, Tatiana, Roth, Michael G., Farmer, Pat, White, Michael A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585813/
https://www.ncbi.nlm.nih.gov/pubmed/19057677
http://dx.doi.org/10.1371/journal.pgen.1000298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585813/
https://www.ncbi.nlm.nih.gov/pubmed/19057677
http://dx.doi.org/10.1371/journal.pgen.1000298

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