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Identification of Channel-lining Amino Acid Residues in the Hydrophobic Segment of Colicin Ia
Colicin Ia is a bactericidal protein of 626 amino acid residues that kills its target cell by forming a channel in the inner membrane; it can also form voltage-dependent channels in planar lipid bilayer membranes. The channel-forming activity resides in the carboxy-terminal domain of ∼177 residues....
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585860/ https://www.ncbi.nlm.nih.gov/pubmed/19029376 http://dx.doi.org/10.1085/jgp.200810042 |