Cargando…
Regulation of Bestrophin Cl Channels by Calcium: Role of the C Terminus
Human bestrophin-1 (hBest1), which is genetically linked to several kinds of retinopathy and macular degeneration in both humans and dogs, is the founding member of a family of Cl(−) ion channels that are activated by intracellular Ca(2+). At present, the structures and mechanisms responsible for Ca...
Autores principales: | Xiao, Qinghuan, Prussia, Andrew, Yu, Kuai, Cui, Yuan-yuan, Hartzell, H. Criss |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585866/ https://www.ncbi.nlm.nih.gov/pubmed/19029375 http://dx.doi.org/10.1085/jgp.200810056 |
Ejemplares similares
-
Single Cl(−) Channels Activated by Ca(2+) in Drosophila S2 Cells Are Mediated By Bestrophins
por: Chien, Li-Ting, et al.
Publicado: (2006) -
Drosophila Bestrophin-1 Chloride Current Is Dually Regulated by Calcium and Cell Volume
por: Chien, Li-Ting, et al.
Publicado: (2007) -
Mouse Bestrophin-2 Is a Bona fide Cl(−) Channel: Identification of a Residue Important in Anion Binding and Conduction
por: Qu, Zhiqiang, et al.
Publicado: (2004) -
Determinants of Anion Permeation in the Second Transmembrane Domain of the Mouse Bestrophin-2 Chloride Channel
por: Qu, Zhiqiang, et al.
Publicado: (2004) -
Rescue of Volume-regulated Anion Current by Bestrophin Mutants with Altered Charge Selectivity
por: Chien, Li-Ting, et al.
Publicado: (2008)