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An optimized procedure for the design and evaluation of Ecotilling assays

BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most common form of genetic variability in the human genome and play a prominent role in the heritability of phenotypes. Especially rare alleles with frequencies less than 5% may exhibit a particularly strong influence on the development of...

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Detalles Bibliográficos
Autores principales: Coassin, Stefan, Brandstätter, Anita, Kronenberg, Florian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586031/
https://www.ncbi.nlm.nih.gov/pubmed/18973671
http://dx.doi.org/10.1186/1471-2164-9-510