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Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM
The accuracy of ribosomal translation is achieved by an initial selection and a proofreading step, mediated by EF-Tu, which forms a ternary complex with aminoacyl(aa)-tRNA. To study the binding modes of different aa-tRNAs, we compared cryo-EM maps of the kirromycin-stalled ribosome bound with ternar...
Autores principales: | Li, Wen, Agirrezabala, Xabier, Lei, Jianlin, Bouakaz, Lamine, Brunelle, Julie L, Ortiz-Meoz, Rodrigo F, Green, Rachel, Sanyal, Suparna, Ehrenberg, Måns, Frank, Joachim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586802/ https://www.ncbi.nlm.nih.gov/pubmed/19020518 http://dx.doi.org/10.1038/emboj.2008.243 |
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