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Telomeric Position Effect—A Third Silencing Mechanism in Eukaryotes

Eukaryotic chromosomes terminate in telomeres, complex nucleoprotein structures that are required for chromosome integrity that are implicated in cellular senescence and cancer. The chromatin at the telomere is unique with characteristics of both heterochromatin and euchromatin. The end of the chrom...

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Detalles Bibliográficos
Autores principales: Doheny, J. Greg, Mottus, Randy, Grigliatti, Thomas A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587703/
https://www.ncbi.nlm.nih.gov/pubmed/19057646
http://dx.doi.org/10.1371/journal.pone.0003864