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Telomeric Position Effect—A Third Silencing Mechanism in Eukaryotes
Eukaryotic chromosomes terminate in telomeres, complex nucleoprotein structures that are required for chromosome integrity that are implicated in cellular senescence and cancer. The chromatin at the telomere is unique with characteristics of both heterochromatin and euchromatin. The end of the chrom...
Autores principales: | Doheny, J. Greg, Mottus, Randy, Grigliatti, Thomas A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587703/ https://www.ncbi.nlm.nih.gov/pubmed/19057646 http://dx.doi.org/10.1371/journal.pone.0003864 |
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