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Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide

BACKGROUND: Prions, the infectious agents that cause transmissible spongiform encephalopathies (TSEs), are relatively resistant to destruction by physical, enzymatic, and chemical treatments. Hydrolysis in boiling saturated calcium hydroxide (limewater) utilizes inexpensive chemicals to digest prote...

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Detalles Bibliográficos
Autores principales: Greenlee, Justin J, Nicholson, Eric M, Hamir, Amir N, Noyes, Gary P, Holtzapple, Mark T, Kehrli, Marcus E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588617/
https://www.ncbi.nlm.nih.gov/pubmed/18957103
http://dx.doi.org/10.1186/1756-0500-1-99

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