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Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide
BACKGROUND: Prions, the infectious agents that cause transmissible spongiform encephalopathies (TSEs), are relatively resistant to destruction by physical, enzymatic, and chemical treatments. Hydrolysis in boiling saturated calcium hydroxide (limewater) utilizes inexpensive chemicals to digest prote...
Autores principales: | Greenlee, Justin J, Nicholson, Eric M, Hamir, Amir N, Noyes, Gary P, Holtzapple, Mark T, Kehrli, Marcus E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588617/ https://www.ncbi.nlm.nih.gov/pubmed/18957103 http://dx.doi.org/10.1186/1756-0500-1-99 |
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