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Association of Epstein-Barr virus with an angioimmunoblastic lymphadenopathy-like lymphoproliferative syndrome.

A patient presented with fever, night sweats, generalized lymphadenopathy, cold agglutinin hemolytic anemia, and thrombocytopenia. Lymph node biopsy revealed a lymphoplasmacytic infiltrate sparing the cortical sinuses but associated with arborizing blood vessels. Epstein-Barr virus (EBV) DNA was dem...

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Detalles Bibliográficos
Autores principales: White, A. C., Katz, B. Z., Silbert, J. A.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589124/
https://www.ncbi.nlm.nih.gov/pubmed/2554599
Descripción
Sumario:A patient presented with fever, night sweats, generalized lymphadenopathy, cold agglutinin hemolytic anemia, and thrombocytopenia. Lymph node biopsy revealed a lymphoplasmacytic infiltrate sparing the cortical sinuses but associated with arborizing blood vessels. Epstein-Barr virus (EBV) DNA was demonstrated in tissue from an involved lymph node. These data suggest an association of EBV with a lymphoproliferative process that resembles angioimmunoblastic lymphadenopathy with dysproteinemia.