The switch between EBV latency and replication.

This paper reviews experiments done in the author's laboratory which led to the discovery of an Epstein-Barr virus (EBV) gene, BZLF1, whose product, ZEBRA, switches the virus from latency to the replicative phase of its life cycle. Recent experiments are summarized which explore the effects of...

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Detalles Bibliográficos
Autor principal: Miller, G.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589219/
https://www.ncbi.nlm.nih.gov/pubmed/2549738
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author Miller, G.
author_facet Miller, G.
author_sort Miller, G.
collection PubMed
description This paper reviews experiments done in the author's laboratory which led to the discovery of an Epstein-Barr virus (EBV) gene, BZLF1, whose product, ZEBRA, switches the virus from latency to the replicative phase of its life cycle. Recent experiments are summarized which explore the effects of EBV genome rearrangements and cell background on the expression of ZEBRA, and which investigate the viral targets of ZEBRA action.
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spelling pubmed-25892192008-11-28 The switch between EBV latency and replication. Miller, G. Yale J Biol Med Research Article This paper reviews experiments done in the author's laboratory which led to the discovery of an Epstein-Barr virus (EBV) gene, BZLF1, whose product, ZEBRA, switches the virus from latency to the replicative phase of its life cycle. Recent experiments are summarized which explore the effects of EBV genome rearrangements and cell background on the expression of ZEBRA, and which investigate the viral targets of ZEBRA action. Yale Journal of Biology and Medicine 1989 /pmc/articles/PMC2589219/ /pubmed/2549738 Text en
spellingShingle Research Article
Miller, G.
The switch between EBV latency and replication.
title The switch between EBV latency and replication.
title_full The switch between EBV latency and replication.
title_fullStr The switch between EBV latency and replication.
title_full_unstemmed The switch between EBV latency and replication.
title_short The switch between EBV latency and replication.
title_sort switch between ebv latency and replication.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589219/
https://www.ncbi.nlm.nih.gov/pubmed/2549738
work_keys_str_mv AT millerg theswitchbetweenebvlatencyandreplication
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