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Modulation of host defense by the neuropeptide alpha-MSH.
alpha-melanocyte stimulating hormone (alpha-MSH), a peptide that occurs within the brain, the circulation, and other body sites, is a potent antipyretic agent when given centrally or peripherally. The peptide likewise inhibits inflammation and aspects of the acute-phase response. The combined eviden...
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Formato: | Texto |
Lenguaje: | English |
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Yale Journal of Biology and Medicine
1990
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589306/ https://www.ncbi.nlm.nih.gov/pubmed/2205057 |
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author | Lipton, J. M. |
author_facet | Lipton, J. M. |
author_sort | Lipton, J. M. |
collection | PubMed |
description | alpha-melanocyte stimulating hormone (alpha-MSH), a peptide that occurs within the brain, the circulation, and other body sites, is a potent antipyretic agent when given centrally or peripherally. The peptide likewise inhibits inflammation and aspects of the acute-phase response. The combined evidence suggests that alpha-MSH molecules act as natural modulators of host reactions by antagonizing the central and peripheral actions of cytokines. |
format | Text |
id | pubmed-2589306 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1990 |
publisher | Yale Journal of Biology and Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-25893062008-11-28 Modulation of host defense by the neuropeptide alpha-MSH. Lipton, J. M. Yale J Biol Med Research Article alpha-melanocyte stimulating hormone (alpha-MSH), a peptide that occurs within the brain, the circulation, and other body sites, is a potent antipyretic agent when given centrally or peripherally. The peptide likewise inhibits inflammation and aspects of the acute-phase response. The combined evidence suggests that alpha-MSH molecules act as natural modulators of host reactions by antagonizing the central and peripheral actions of cytokines. Yale Journal of Biology and Medicine 1990 /pmc/articles/PMC2589306/ /pubmed/2205057 Text en |
spellingShingle | Research Article Lipton, J. M. Modulation of host defense by the neuropeptide alpha-MSH. |
title | Modulation of host defense by the neuropeptide alpha-MSH. |
title_full | Modulation of host defense by the neuropeptide alpha-MSH. |
title_fullStr | Modulation of host defense by the neuropeptide alpha-MSH. |
title_full_unstemmed | Modulation of host defense by the neuropeptide alpha-MSH. |
title_short | Modulation of host defense by the neuropeptide alpha-MSH. |
title_sort | modulation of host defense by the neuropeptide alpha-msh. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589306/ https://www.ncbi.nlm.nih.gov/pubmed/2205057 |
work_keys_str_mv | AT liptonjm modulationofhostdefensebytheneuropeptidealphamsh |