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Erythropoietin: current status.
Understanding the regulation of red blood cell production has been greatly enhanced by the cloning and expression of the gene for human erythropoietin (Epo) and its receptor. The availability of recombinant human erythropoietin (rhEpo) for administration to patients has ushered in a new era in molec...
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Formato: | Texto |
Lenguaje: | English |
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Yale Journal of Biology and Medicine
1990
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589359/ https://www.ncbi.nlm.nih.gov/pubmed/2293499 |
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author | Bunn, H. F. |
author_facet | Bunn, H. F. |
author_sort | Bunn, H. F. |
collection | PubMed |
description | Understanding the regulation of red blood cell production has been greatly enhanced by the cloning and expression of the gene for human erythropoietin (Epo) and its receptor. The availability of recombinant human erythropoietin (rhEpo) for administration to patients has ushered in a new era in molecular medicine. Intravenous or subcutaneous administration of rhEpo can reliably cure the anemia of chronic renal failure and may be effective in the treatment of anemias secondary to chronic inflammation, malignancy, and marrow suppression from chemotherapy. In addition, rhEpo therapy will probably play a prominent role in transfusion medicine, both in preparing patients for auto-transfusions as well as in minimizing red cell transfusion requirements in the post-operative period. |
format | Text |
id | pubmed-2589359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1990 |
publisher | Yale Journal of Biology and Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-25893592008-11-28 Erythropoietin: current status. Bunn, H. F. Yale J Biol Med Research Article Understanding the regulation of red blood cell production has been greatly enhanced by the cloning and expression of the gene for human erythropoietin (Epo) and its receptor. The availability of recombinant human erythropoietin (rhEpo) for administration to patients has ushered in a new era in molecular medicine. Intravenous or subcutaneous administration of rhEpo can reliably cure the anemia of chronic renal failure and may be effective in the treatment of anemias secondary to chronic inflammation, malignancy, and marrow suppression from chemotherapy. In addition, rhEpo therapy will probably play a prominent role in transfusion medicine, both in preparing patients for auto-transfusions as well as in minimizing red cell transfusion requirements in the post-operative period. Yale Journal of Biology and Medicine 1990 /pmc/articles/PMC2589359/ /pubmed/2293499 Text en |
spellingShingle | Research Article Bunn, H. F. Erythropoietin: current status. |
title | Erythropoietin: current status. |
title_full | Erythropoietin: current status. |
title_fullStr | Erythropoietin: current status. |
title_full_unstemmed | Erythropoietin: current status. |
title_short | Erythropoietin: current status. |
title_sort | erythropoietin: current status. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589359/ https://www.ncbi.nlm.nih.gov/pubmed/2293499 |
work_keys_str_mv | AT bunnhf erythropoietincurrentstatus |