Isolated production of aldosterone by a malignant adrenal carcinoma.

A 45-year-old female developed hypertension and hypokalemia. Elevated plasma aldosterone and suppressed plasma renin levels were measured with no evidence for glucocorticoid or androgen abnormalities. A left adrenal tumor was removed that showed histologic criteria for malignancy. It is commonly tau...

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Detalles Bibliográficos
Autores principales: Levine, D. S., Fischer, D. G., Forman, B. H.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1984
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589781/
https://www.ncbi.nlm.nih.gov/pubmed/6537692
Descripción
Sumario:A 45-year-old female developed hypertension and hypokalemia. Elevated plasma aldosterone and suppressed plasma renin levels were measured with no evidence for glucocorticoid or androgen abnormalities. A left adrenal tumor was removed that showed histologic criteria for malignancy. It is commonly taught that malignant adrenal tumors are recognized by their multiple hormone production. However, isolated aldosterone production by a carcinoma can occur and requires close follow-up observation and therapy for this highly malignant tumor.

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