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The GABA hypothesis of the pathogenesis of hepatic encephalopathy: current status.
Gamma-aminobutyric acid (GABA), the principal inhibitory neurotransmitter of the mammalian brain, can induce coma. Outside the central nervous system it is synthesized by gut bacteria and catabolized largely in the liver. GABA and its agonists, as well as benzodiazepines and barbiturates, induce neu...
Autores principales: | Jones, E. A., Schafer, D. F., Ferenci, P., Pappas, S. C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Yale Journal of Biology and Medicine
1984
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589853/ https://www.ncbi.nlm.nih.gov/pubmed/6093394 |
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