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Peptide neuroregulators: the opioid system as a model.

Aaron Lerner's work provides a stunning set of examples of substances that help to transmit information in the brain and body. His characterization of alpha-MSH and melatonin and his sparking of interest in the further discovery of previously unknown substances have been of inestimable value fo...

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Detalles Bibliográficos
Autores principales: Barchas, J. D., Evans, C., Elliott, G. R., Berger, P. A.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1985
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589971/
https://www.ncbi.nlm.nih.gov/pubmed/2938344
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author Barchas, J. D.
Evans, C.
Elliott, G. R.
Berger, P. A.
author_facet Barchas, J. D.
Evans, C.
Elliott, G. R.
Berger, P. A.
author_sort Barchas, J. D.
collection PubMed
description Aaron Lerner's work provides a stunning set of examples of substances that help to transmit information in the brain and body. His characterization of alpha-MSH and melatonin and his sparking of interest in the further discovery of previously unknown substances have been of inestimable value for the field of neurobiology. Efforts such as those that Lerner undertook so successfully in the field of investigative dermatology now constitute a major research thrust in the field of behavioral neurochemistry and are directly related to advances in psychiatry and neurology. This review considers aspects of research on the neuropeptides, with particular attention to the endogenous opioid (morphine-like) peptides that are active on neural tissue. Neuropeptide research can be categorized broadly as efforts to discover and characterize new families and classes of active agents, investigations of their genetic and molecular processing, and studies of their relationships to behavior in animals and human beings. This review selectively considers some key research questions and strategies that arise from such research.
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spelling pubmed-25899712008-11-28 Peptide neuroregulators: the opioid system as a model. Barchas, J. D. Evans, C. Elliott, G. R. Berger, P. A. Yale J Biol Med Research Article Aaron Lerner's work provides a stunning set of examples of substances that help to transmit information in the brain and body. His characterization of alpha-MSH and melatonin and his sparking of interest in the further discovery of previously unknown substances have been of inestimable value for the field of neurobiology. Efforts such as those that Lerner undertook so successfully in the field of investigative dermatology now constitute a major research thrust in the field of behavioral neurochemistry and are directly related to advances in psychiatry and neurology. This review considers aspects of research on the neuropeptides, with particular attention to the endogenous opioid (morphine-like) peptides that are active on neural tissue. Neuropeptide research can be categorized broadly as efforts to discover and characterize new families and classes of active agents, investigations of their genetic and molecular processing, and studies of their relationships to behavior in animals and human beings. This review selectively considers some key research questions and strategies that arise from such research. Yale Journal of Biology and Medicine 1985 /pmc/articles/PMC2589971/ /pubmed/2938344 Text en
spellingShingle Research Article
Barchas, J. D.
Evans, C.
Elliott, G. R.
Berger, P. A.
Peptide neuroregulators: the opioid system as a model.
title Peptide neuroregulators: the opioid system as a model.
title_full Peptide neuroregulators: the opioid system as a model.
title_fullStr Peptide neuroregulators: the opioid system as a model.
title_full_unstemmed Peptide neuroregulators: the opioid system as a model.
title_short Peptide neuroregulators: the opioid system as a model.
title_sort peptide neuroregulators: the opioid system as a model.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589971/
https://www.ncbi.nlm.nih.gov/pubmed/2938344
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AT elliottgr peptideneuroregulatorstheopioidsystemasamodel
AT bergerpa peptideneuroregulatorstheopioidsystemasamodel