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Peptide neuroregulators: the opioid system as a model.
Aaron Lerner's work provides a stunning set of examples of substances that help to transmit information in the brain and body. His characterization of alpha-MSH and melatonin and his sparking of interest in the further discovery of previously unknown substances have been of inestimable value fo...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Yale Journal of Biology and Medicine
1985
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589971/ https://www.ncbi.nlm.nih.gov/pubmed/2938344 |
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author | Barchas, J. D. Evans, C. Elliott, G. R. Berger, P. A. |
author_facet | Barchas, J. D. Evans, C. Elliott, G. R. Berger, P. A. |
author_sort | Barchas, J. D. |
collection | PubMed |
description | Aaron Lerner's work provides a stunning set of examples of substances that help to transmit information in the brain and body. His characterization of alpha-MSH and melatonin and his sparking of interest in the further discovery of previously unknown substances have been of inestimable value for the field of neurobiology. Efforts such as those that Lerner undertook so successfully in the field of investigative dermatology now constitute a major research thrust in the field of behavioral neurochemistry and are directly related to advances in psychiatry and neurology. This review considers aspects of research on the neuropeptides, with particular attention to the endogenous opioid (morphine-like) peptides that are active on neural tissue. Neuropeptide research can be categorized broadly as efforts to discover and characterize new families and classes of active agents, investigations of their genetic and molecular processing, and studies of their relationships to behavior in animals and human beings. This review selectively considers some key research questions and strategies that arise from such research. |
format | Text |
id | pubmed-2589971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1985 |
publisher | Yale Journal of Biology and Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-25899712008-11-28 Peptide neuroregulators: the opioid system as a model. Barchas, J. D. Evans, C. Elliott, G. R. Berger, P. A. Yale J Biol Med Research Article Aaron Lerner's work provides a stunning set of examples of substances that help to transmit information in the brain and body. His characterization of alpha-MSH and melatonin and his sparking of interest in the further discovery of previously unknown substances have been of inestimable value for the field of neurobiology. Efforts such as those that Lerner undertook so successfully in the field of investigative dermatology now constitute a major research thrust in the field of behavioral neurochemistry and are directly related to advances in psychiatry and neurology. This review considers aspects of research on the neuropeptides, with particular attention to the endogenous opioid (morphine-like) peptides that are active on neural tissue. Neuropeptide research can be categorized broadly as efforts to discover and characterize new families and classes of active agents, investigations of their genetic and molecular processing, and studies of their relationships to behavior in animals and human beings. This review selectively considers some key research questions and strategies that arise from such research. Yale Journal of Biology and Medicine 1985 /pmc/articles/PMC2589971/ /pubmed/2938344 Text en |
spellingShingle | Research Article Barchas, J. D. Evans, C. Elliott, G. R. Berger, P. A. Peptide neuroregulators: the opioid system as a model. |
title | Peptide neuroregulators: the opioid system as a model. |
title_full | Peptide neuroregulators: the opioid system as a model. |
title_fullStr | Peptide neuroregulators: the opioid system as a model. |
title_full_unstemmed | Peptide neuroregulators: the opioid system as a model. |
title_short | Peptide neuroregulators: the opioid system as a model. |
title_sort | peptide neuroregulators: the opioid system as a model. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589971/ https://www.ncbi.nlm.nih.gov/pubmed/2938344 |
work_keys_str_mv | AT barchasjd peptideneuroregulatorstheopioidsystemasamodel AT evansc peptideneuroregulatorstheopioidsystemasamodel AT elliottgr peptideneuroregulatorstheopioidsystemasamodel AT bergerpa peptideneuroregulatorstheopioidsystemasamodel |