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Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

BACKGROUND: In mammals the parental genomes are epigenetically reprogrammed after fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm-derived) chromosomes prior to DNA replication in zygotes. Such active DNA demethylation in the zygote has been documented for seve...

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Detalles Bibliográficos
Autores principales:	Lepikhov, Konstantin, Zakhartchenko, Valeri, Hao, Ru, Yang, Feikun, Wrenzycki, Christine, Niemann, Heiner, Wolf, Eckhard, Walter, Joern
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590599/ https://www.ncbi.nlm.nih.gov/pubmed/19014417 http://dx.doi.org/10.1186/1756-8935-1-8

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