Cargando…

Differential neuroglycan C expression during retinal degeneration in Rpe65(−/−) mice

PURPOSE: An increased mRNA expression of the genes coding for the extracellular matrix proteins neuroglycan C (NGC), interphotoreceptor matrix proteoglycan 2 (IMPG2), and CD44 antigen (CD44) has been observed during retinal degeneration in mice with a targeted disruption of the Rpe65 gene (Rpe65(−/−...

Descripción completa

Detalles Bibliográficos
Autores principales:	Escher, Pascal, Cottet, Sandra, Aono, Saichiko, Oohira, Atsuhiko, Schorderet, Daniel F.
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592529/ https://www.ncbi.nlm.nih.gov/pubmed/19050768

Ejemplares similares

Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/ chondroitin sulfate proteoglycan 5
por: Cottet, Sandra, et al.
Publicado: (2013)

Altered expression of β-galactosidase-1-like protein 3 (Glb1l3) in the retinal pigment epithelium (RPE)-specific 65-kDa protein knock-out mouse model of Leber’s congenital amaurosis
por: Le Carré, Joane, et al.
Publicado: (2011)

The findings of optical coherence tomography of retinal degeneration in relation to the morphological and electroretinographic features in RPE65(−/−) mice
por: Tanabu, Reiko, et al.
Publicado: (2019)

Retinal Structure in RPE65-Associated Retinal Dystrophy
por: Kumaran, Neruban, et al.
Publicado: (2020)

Cost Effectiveness of Voretigene Neparvovec for RPE65-Mediated Inherited Retinal Degeneration in Germany
por: Uhrmann, Matthias Fritz, et al.
Publicado: (2020)

A Molecular Genetic Analysis of RPE65-Associated Forms of Inherited Retinal Degenerations in the Russian Federation
por: Stepanova, Anna, et al.
Publicado: (2023)

Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration
por: Pyakurel, Aswin, et al.
Publicado: (2017)

Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration
por: Qi, Xiaoping, et al.
Publicado: (2017)

The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration
por: Wang, Yuhong, et al.
Publicado: (2022)

Voretigene Neparvovec for the Treatment of RPE65-associated Retinal Dystrophy: Consensus and Recommendations from the Korea RPE65-IRD Consensus Paper Committee
por: Han, Jinu, et al.
Publicado: (2023)

Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice With the RPE65 Leu450Met Variant is Associated With Oxidative Stress and Apoptosis
por: Zhong, Xin, et al.
Publicado: (2016)

Long-Term Follow-Up of Retinal Degenerations Associated With LRAT Mutations and Their Comparability to Phenotypes Associated With RPE65 Mutations
por: Talib, Mays, et al.
Publicado: (2019)

A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs
por: Annear, Matthew J, et al.
Publicado: (2021)

Frequency of RPE65 Gene Mutation in Patients with Hereditary Retinal Dystrophy
por: Sinim Kahraman, Neslihan, et al.
Publicado: (2022)

Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7
por: Zhang, Youwen, et al.
Publicado: (2017)

Selective Ablation of Dehydrodolichyl Diphosphate Synthase in Murine Retinal Pigment Epithelium (RPE) Causes RPE Atrophy and Retinal Degeneration
por: DeRamus, Marci L., et al.
Publicado: (2020)

Novel mutations in RPE65 identified in consanguineous Pakistani families with retinal dystrophy
por: Kabir, Firoz, et al.
Publicado: (2013)

The clinical features of retinal disease due to a dominant mutation in RPE65
por: Hull, Sarah, et al.
Publicado: (2016)

Bax-Induced Apoptosis in Leber's Congenital Amaurosis: A Dual Role in Rod and Cone Degeneration
por: Hamann, Séverine, et al.
Publicado: (2009)

Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells
por: Nash, Benjamin M., et al.
Publicado: (2021)

Validation of a Vision-Guided Mobility Assessment for RPE65-Associated Retinal Dystrophy
por: Kumaran, Neruban, et al.
Publicado: (2020)

The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation
por: Wu, Wenjing, et al.
Publicado: (2022)

RPE65-associated inherited retinal diseases: consensus recommendations for eligibility to gene therapy
por: Sodi, Andrea, et al.
Publicado: (2021)

Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model
por: Armento, Angela, et al.
Publicado: (2021)

Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level
por: Udry, Florian, et al.
Publicado: (2020)

M-opsin protein degradation is inhibited by MG-132 in Rpe65(−/−) retinal explant culture
por: Sato, Kota, et al.
Publicado: (2012)

Early onset flecked retinal dystrophy associated with new compound heterozygous RPE65 variants
por: Katagiri, Satoshi, et al.
Publicado: (2018)

Inherited Retinal Diseases Due to RPE65 Variants: From Genetic Diagnostic Management to Therapy
por: Aoun, Manar, et al.
Publicado: (2021)

Short-Term Outcomes of the First in Vivo Gene Therapy for RPE65-Mediated Retinitis Pigmentosa
por: Kwak, Jay Jiyong, et al.
Publicado: (2022)

Long-Term Follow-Up of a Family with Retinal Dystrophy Caused by RPE65 Mutation
por: Jánossy, Ágnes, et al.
Publicado: (2023)

Epidemiology of Mutations in the 65-kDa Retinal Pigment Epithelium (RPE65) Gene-Mediated Inherited Retinal Dystrophies: A Systematic Literature Review
por: Sallum, Juliana M. F., et al.
Publicado: (2022)

Hydroquinone predisposes for retinal pigment epithelial (RPE) cell degeneration in inflammatory conditions
por: Bhattarai, Niina, et al.
Publicado: (2022)

DAPL1 deficiency in mice impairs antioxidant defenses in the RPE and leads to retinal degeneration with AMD-like features
por: Ma, Xiaoyin, et al.
Publicado: (2023)

Prospect of retinal gene therapy following commercialization of voretigene neparvovec-rzyl for retinal dystrophy mediated by RPE65 mutation
por: Ameri, Hossein
Publicado: (2018)

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65-Associated Leber Congenital Amaurosis
por: Kumaran, Neruban, et al.
Publicado: (2018)

Phenotypic expansion of autosomal dominant retinitis pigmentosa associated with the D477G mutation in RPE65
por: Jauregui, Ruben, et al.
Publicado: (2020)

An Economic Evaluation of Voretigene Neparvovec for the Treatment of Biallelic RPE65-Mediated Inherited Retinal Dystrophies in the UK
por: Viriato, Daniel, et al.
Publicado: (2020)

Cost-effectiveness of voretigene neparvovec in the treatment of patients with inherited retinal disease with RPE65 mutation in Switzerland
por: Bhadhuri, Arjun, et al.
Publicado: (2022)

Computational studies for the structure and function of mRPE65
por: Guo, Hao, et al.
Publicado: (2007)

Late presentation of RPE65 retinopathy in three siblings
por: Magliyah, Moustafa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mg5enoeq3k0okgrhbd6jmm5t7j