The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

PrP(Sc), a misfolded and aggregated form of the cellular prion protein PrP(C), is the only defined constituent of the transmissible agent causing prion diseases. Expression of PrP(C) in the host organism is necessary for prion replication and for prion neurotoxicity. Understanding prion diseases nec...

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Detalles Bibliográficos
Autores principales: Polymenidou, Magdalini, Moos, Rita, Scott, Mike, Sigurdson, Christina, Shi, Yong-zhong, Yajima, Bill, Hafner-Bratkovič, Iva, Jerala, Roman, Hornemann, Simone, Wuthrich, Kurt, Bellon, Anne, Vey, Martin, Garen, Graciela, James, Michael N. G., Kav, Nat, Aguzzi, Adriano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592702/
https://www.ncbi.nlm.nih.gov/pubmed/19060956
http://dx.doi.org/10.1371/journal.pone.0003872

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