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Early Detection of Erlotinib Treatment Response in NSCLC by 3′-Deoxy-3′-[(18)F]-Fluoro-L-Thymidine ([(18)F]FLT) Positron Emission Tomography (PET)
BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations of EGFR were found in lung adenocarcinoma that lead to exquisite dependency on EGFR signaling; thus patients with EGFR-muta...
Autores principales: | Ullrich, Roland T., Zander, Thomas, Neumaier, Bernd, Koker, Mirjam, Shimamura, Takeshi, Waerzeggers, Yannic, Borgman, Christa L., Tawadros, Samir, Li, Hongfeng, Sos, Martin L., Backes, Heiko, Shapiro, Geoffrey I., Wolf, Jürgen, Jacobs, Andreas H., Thomas, Roman K., Winkeler, Alexandra |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592703/ https://www.ncbi.nlm.nih.gov/pubmed/19079597 http://dx.doi.org/10.1371/journal.pone.0003908 |
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