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The telosome/shelterin complex and its functions
The telomeres that cap the ends of eukaryotic chromosomes serve a dual role in protecting the chromosome ends and in intracellular signaling for regulating cell proliferation. A complex of six telomere-associated proteins has been identified - the telosome or shelterin complex - that is crucial for...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592706/ https://www.ncbi.nlm.nih.gov/pubmed/18828880 http://dx.doi.org/10.1186/gb-2008-9-9-232 |
| _version_ | 1782161561889013760 |
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| author | Xin, Huawei Liu, Dan Songyang, Zhou |
| author_facet | Xin, Huawei Liu, Dan Songyang, Zhou |
| author_sort | Xin, Huawei |
| collection | PubMed |
| description | The telomeres that cap the ends of eukaryotic chromosomes serve a dual role in protecting the chromosome ends and in intracellular signaling for regulating cell proliferation. A complex of six telomere-associated proteins has been identified - the telosome or shelterin complex - that is crucial for both the maintenance of telomere structure and its signaling functions. |
| format | Text |
| id | pubmed-2592706 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-25927062009-09-18 The telosome/shelterin complex and its functions Xin, Huawei Liu, Dan Songyang, Zhou Genome Biol Review The telomeres that cap the ends of eukaryotic chromosomes serve a dual role in protecting the chromosome ends and in intracellular signaling for regulating cell proliferation. A complex of six telomere-associated proteins has been identified - the telosome or shelterin complex - that is crucial for both the maintenance of telomere structure and its signaling functions. BioMed Central 2008 2008-09-18 /pmc/articles/PMC2592706/ /pubmed/18828880 http://dx.doi.org/10.1186/gb-2008-9-9-232 Text en Copyright © 2008 BioMed Central Ltd |
| spellingShingle | Review Xin, Huawei Liu, Dan Songyang, Zhou The telosome/shelterin complex and its functions |
| title | The telosome/shelterin complex and its functions |
| title_full | The telosome/shelterin complex and its functions |
| title_fullStr | The telosome/shelterin complex and its functions |
| title_full_unstemmed | The telosome/shelterin complex and its functions |
| title_short | The telosome/shelterin complex and its functions |
| title_sort | telosome/shelterin complex and its functions |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592706/ https://www.ncbi.nlm.nih.gov/pubmed/18828880 http://dx.doi.org/10.1186/gb-2008-9-9-232 |
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