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The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation
INTRODUCTION: The treatment of septic conditions in critically ill patients is still one of medicine's major challenges. Cyclic nucleotides, adenosine and its receptors play a pivotal role in the regulation of inflammatory responses and in limiting inflammatory tissue destruction. The aim of th...
Autores principales: | Kayhan, Nalan, Funke, Benjamin, Conzelmann, Lars Oliver, Winkler, Harald, Hofer, Stefan, Steppan, Jochen, Schmidt, Heinfried, Bardenheuer, Hubert, Vahl, Christian-Friedrich, Weigand, Markus A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592762/ https://www.ncbi.nlm.nih.gov/pubmed/18847498 http://dx.doi.org/10.1186/cc7033 |
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