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4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

INTRODUCTION: 4-Hydroxynonenal (HNE) is one of the most abundant and reactive aldehydes of lipid peroxidation products and exerts various effects on intracellular and extracellular signalling cascades. We have previously shown that HNE at low concentrations could be considered as an important mediat...

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Detalles Bibliográficos
Autores principales:	Vaillancourt, France, Fahmi, Hassan, Shi, Qin, Lavigne, Patrick, Ranger, Pierre, Fernandes, Julio C, Benderdour, Mohamed
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592788/ https://www.ncbi.nlm.nih.gov/pubmed/18782442 http://dx.doi.org/10.1186/ar2503

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