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Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints

INTRODUCTION: Chondrocytes have to withstand considerable hypoxic conditions within the avascular articular cartilage. The present study investigated the effects of inhibiting or stabilizing hypoxia-inducible factor (HIF)-1α by 2-methoxyestradiol or dimethyloxaloylglycine on the progression of osteo...

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Detalles Bibliográficos
Autores principales:	Gelse, Kolja, Pfander, David, Obier, Simon, Knaup, Karl X, Wiesener, Michael, Hennig, Friedrich F, Swoboda, Bernd
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592793/ https://www.ncbi.nlm.nih.gov/pubmed/18789153 http://dx.doi.org/10.1186/ar2508

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