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CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation–transcription coupling
Communication between cell surface proteins and the nucleus is integral to many cellular adaptations. In the case of ion channels in excitable cells, the dynamics of signaling to the nucleus are particularly important because the natural stimulus, surface membrane depolarization, is rapidly pulsatil...
Autores principales: | Wheeler, Damian G., Barrett, Curtis F., Groth, Rachel D., Safa, Parsa, Tsien, Richard W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592819/ https://www.ncbi.nlm.nih.gov/pubmed/19047462 http://dx.doi.org/10.1083/jcb.200805048 |
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