Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Cellular responses to both physiological and pathological DNA double-strand breaks are initiated through activation of the evolutionarily conserved ataxia telangiectasia mutated (ATM) kinase. Upon DNA damage, an activation mechanism involving autophosphorylation has been reported to allow ATM to pho...

Descripción completa

Detalles Bibliográficos
Autores principales: Daniel, Jeremy A., Pellegrini, Manuela, Lee, Ji-Hoon, Paull, Tanya T., Feigenbaum, Lionel, Nussenzweig, André
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592823/
https://www.ncbi.nlm.nih.gov/pubmed/19047460
http://dx.doi.org/10.1083/jcb.200805154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592823/
https://www.ncbi.nlm.nih.gov/pubmed/19047460
http://dx.doi.org/10.1083/jcb.200805154

Ejemplares similares