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Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis
Cytoplasmic dynein functions at several sites during mitosis; however, the basis of targeting to each site remains unclear. Tandem mass spectrometry analysis of mitotic dynein revealed a phosphorylation site in the dynein intermediate chains (ICs) that mediates binding to kinetochores. IC phosphoryl...
Autores principales: | Whyte, Jacqueline, Bader, Jason R., Tauhata, Sinji B.F., Raycroft, Maurice, Hornick, Jessica, Pfister, K. Kevin, Lane, William S., Chan, Gordon K., Hinchcliffe, Edward H., Vaughan, Patricia S., Vaughan, Kevin T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592828/ https://www.ncbi.nlm.nih.gov/pubmed/19029334 http://dx.doi.org/10.1083/jcb.200804114 |
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