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Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding
Newly generated actin free barbed ends at the front of motile cells provide sites for actin filament assembly driving membrane protrusion. Growth factors induce a rapid biphasic increase in actin free barbed ends, and we found both phases absent in fibroblasts lacking H(+) efflux by the Na-H exchang...
Autores principales: | Frantz, Christian, Barreiro, Gabriela, Dominguez, Laura, Chen, Xiaoming, Eddy, Robert, Condeelis, John, Kelly, Mark J.S., Jacobson, Matthew P., Barber, Diane L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592832/ https://www.ncbi.nlm.nih.gov/pubmed/19029335 http://dx.doi.org/10.1083/jcb.200804161 |
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