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Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

Newly generated actin free barbed ends at the front of motile cells provide sites for actin filament assembly driving membrane protrusion. Growth factors induce a rapid biphasic increase in actin free barbed ends, and we found both phases absent in fibroblasts lacking H(+) efflux by the Na-H exchang...

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Detalles Bibliográficos
Autores principales: Frantz, Christian, Barreiro, Gabriela, Dominguez, Laura, Chen, Xiaoming, Eddy, Robert, Condeelis, John, Kelly, Mark J.S., Jacobson, Matthew P., Barber, Diane L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592832/
https://www.ncbi.nlm.nih.gov/pubmed/19029335
http://dx.doi.org/10.1083/jcb.200804161

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