Cargando…
FAM29A promotes microtubule amplification via recruitment of the NEDD1–γ-tubulin complex to the mitotic spindle
Microtubules (MTs) are nucleated from centrosomes and chromatin. In addition, MTs can be generated from preexiting MTs in a γ-tubulin–dependent manner in yeast, plant, and Drosophila cells, although the underlying mechanism remains unknown. Here we show the spindle-associated protein FAM29A promotes...
Autores principales: | Zhu, Hui, Coppinger, Judith A., Jang, Chang-Young, Yates, John R., Fang, Guowei |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592839/ https://www.ncbi.nlm.nih.gov/pubmed/19029337 http://dx.doi.org/10.1083/jcb.200807046 |
Ejemplares similares
-
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement
por: Jang, Chang-Young, et al.
Publicado: (2008) -
Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes
por: Zhu, Zihan, et al.
Publicado: (2023) -
NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
por: Haren, Laurence, et al.
Publicado: (2006) -
A Direct Interaction with NEDD1 Regulates γ-Tubulin Recruitment to the Centrosome
por: Manning, Jantina A., et al.
Publicado: (2010) -
TOG–tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation
por: Byrnes, Amy E., et al.
Publicado: (2017)