A Practical Approach to Quantitate Hepatic Excretory Function

A statistical comparison of different BSP tests was carried out in normal subjects and in patients with various degrees of chronic liver damage. Only the logarithm of the BSP retention correlated linearly with the physiologically more meaningful determination of the maximal excretory capacity of the...

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Detalles Bibliográficos
Autores principales: Bircher, Johannes, Hacki, Walter
Formato: Texto
Lenguaje:English
Publicado: 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595099/
https://www.ncbi.nlm.nih.gov/pubmed/4446630
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author Bircher, Johannes
Hacki, Walter
author_facet Bircher, Johannes
Hacki, Walter
author_sort Bircher, Johannes
collection PubMed
description A statistical comparison of different BSP tests was carried out in normal subjects and in patients with various degrees of chronic liver damage. Only the logarithm of the BSP retention correlated linearly with the physiologically more meaningful determination of the maximal excretory capacity of the liver (BSP Tm, Wheele's method). A double logarithmic transformation was required to correlate the second exponential component of the BSP plasma disappearance curve (k(2)) with the BSP Tm. When the limitations of these methods are kept in mind, the observed statistical relationships can be used to express hepatic functional deterioration in more physiological terms.
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spelling pubmed-25950992008-12-05 A Practical Approach to Quantitate Hepatic Excretory Function Bircher, Johannes Hacki, Walter Yale J Biol Med Articles A statistical comparison of different BSP tests was carried out in normal subjects and in patients with various degrees of chronic liver damage. Only the logarithm of the BSP retention correlated linearly with the physiologically more meaningful determination of the maximal excretory capacity of the liver (BSP Tm, Wheele's method). A double logarithmic transformation was required to correlate the second exponential component of the BSP plasma disappearance curve (k(2)) with the BSP Tm. When the limitations of these methods are kept in mind, the observed statistical relationships can be used to express hepatic functional deterioration in more physiological terms. 1974-09 /pmc/articles/PMC2595099/ /pubmed/4446630 Text en
spellingShingle Articles
Bircher, Johannes
Hacki, Walter
A Practical Approach to Quantitate Hepatic Excretory Function
title A Practical Approach to Quantitate Hepatic Excretory Function
title_full A Practical Approach to Quantitate Hepatic Excretory Function
title_fullStr A Practical Approach to Quantitate Hepatic Excretory Function
title_full_unstemmed A Practical Approach to Quantitate Hepatic Excretory Function
title_short A Practical Approach to Quantitate Hepatic Excretory Function
title_sort practical approach to quantitate hepatic excretory function
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595099/
https://www.ncbi.nlm.nih.gov/pubmed/4446630
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