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Ectopic ACTH syndrome due to pheochromocytoma: case report and review of the literature.

A 51-year-old female was diagnosed preoperatively to have a pheochromocytoma producing ACTH. This diagnosis was based upon her paroxysmal hypertension, hyperpigmentation, and hypokalemia. Elevated levels of serum and urine corticosteroids, plasma ACTH, urinary VMA, and catecholamines fell after a ri...

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Detalles Bibliográficos
Autores principales: Forman, B. H., Marban, E., Kayne, R. D., Passarelli, N. M., Bobrow, S. N., Livolsi, V. A., Merino, M., Minor, M., Farber, L. R.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1979
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595434/
https://www.ncbi.nlm.nih.gov/pubmed/222080
Descripción
Sumario:A 51-year-old female was diagnosed preoperatively to have a pheochromocytoma producing ACTH. This diagnosis was based upon her paroxysmal hypertension, hyperpigmentation, and hypokalemia. Elevated levels of serum and urine corticosteroids, plasma ACTH, urinary VMA, and catecholamines fell after a right adrenal pheochromocytoma was removed. Subsequently this tumor was found to have a high content of ACTH. Review of the literature indicates a mortality rate of 57% for this syndrome. Proper preoperative recognition and management can result in total cure.