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Macromolecular Metabolism in Compensatory Renal Hypertrophy

1. The initial biochemical changes of compensatory hypertrophy occur well within 1 hour of unilateral nephrectomy and perhaps within the first few minutes. 2. The initial increment in rRNA is from decreased metabolism rather than from increased synthesis. 3. Changes in the processing of mRNA precurs...

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Detalles Bibliográficos
Autor principal: Malt, Ronald A.
Formato: Texto
Lenguaje:English
Publicado: 1978
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595727/
https://www.ncbi.nlm.nih.gov/pubmed/366927
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author Malt, Ronald A.
author_facet Malt, Ronald A.
author_sort Malt, Ronald A.
collection PubMed
description 1. The initial biochemical changes of compensatory hypertrophy occur well within 1 hour of unilateral nephrectomy and perhaps within the first few minutes. 2. The initial increment in rRNA is from decreased metabolism rather than from increased synthesis. 3. Changes in the processing of mRNA precursors are probably also important. 4. Compensatory hypertrophy is regulated by a humoral stimulus or stimuli. 5. The stimulus needs to be present virtually all of the time during the early phases of compensatory hypertrophy. 6. The stimulus is related to loss of renal mass, not to loss of renal function.
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spelling pubmed-25957272008-12-05 Macromolecular Metabolism in Compensatory Renal Hypertrophy Malt, Ronald A. Yale J Biol Med Article 1. The initial biochemical changes of compensatory hypertrophy occur well within 1 hour of unilateral nephrectomy and perhaps within the first few minutes. 2. The initial increment in rRNA is from decreased metabolism rather than from increased synthesis. 3. Changes in the processing of mRNA precursors are probably also important. 4. Compensatory hypertrophy is regulated by a humoral stimulus or stimuli. 5. The stimulus needs to be present virtually all of the time during the early phases of compensatory hypertrophy. 6. The stimulus is related to loss of renal mass, not to loss of renal function. 1978 /pmc/articles/PMC2595727/ /pubmed/366927 Text en
spellingShingle Article
Malt, Ronald A.
Macromolecular Metabolism in Compensatory Renal Hypertrophy
title Macromolecular Metabolism in Compensatory Renal Hypertrophy
title_full Macromolecular Metabolism in Compensatory Renal Hypertrophy
title_fullStr Macromolecular Metabolism in Compensatory Renal Hypertrophy
title_full_unstemmed Macromolecular Metabolism in Compensatory Renal Hypertrophy
title_short Macromolecular Metabolism in Compensatory Renal Hypertrophy
title_sort macromolecular metabolism in compensatory renal hypertrophy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595727/
https://www.ncbi.nlm.nih.gov/pubmed/366927
work_keys_str_mv AT maltronalda macromolecularmetabolismincompensatoryrenalhypertrophy