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Age-related appearance of a CMV-specific high-avidity CD8(+ )T cell clonotype which does not occur in young adults
Old age is associated with characteristic changes of the immune system contributing to higher incidence and severity of many infectious diseases. Particularly within the T cell compartment latent infection with human Cytomegalovirus (CMV) is contributing to and accelerating immunosenescence. However...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596076/ https://www.ncbi.nlm.nih.gov/pubmed/19014475 http://dx.doi.org/10.1186/1742-4933-5-14 |