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Age-related appearance of a CMV-specific high-avidity CD8(+ )T cell clonotype which does not occur in young adults

Old age is associated with characteristic changes of the immune system contributing to higher incidence and severity of many infectious diseases. Particularly within the T cell compartment latent infection with human Cytomegalovirus (CMV) is contributing to and accelerating immunosenescence. However...

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Detalles Bibliográficos
Autores principales: Schwanninger, Angelika, Weinberger, Birgit, Weiskopf, Daniela, Herndler-Brandstetter, Dietmar, Reitinger, Stephan, Gassner, Christoph, Schennach, Harald, Parson, Walther, Würzner, Reinhard, Grubeck-Loebenstein, Beatrix
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596076/
https://www.ncbi.nlm.nih.gov/pubmed/19014475
http://dx.doi.org/10.1186/1742-4933-5-14