A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum

BACKGROUND: In recent years, a major increase in the occurrence of drug resistant falciparum malaria has been reported. Choline analogs, such as the bisthiazolium T4, represent a novel class of compounds with strong potency against drug sensitive and resistant P. falciparum clones. Although T4 and i...

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Detalles Bibliográficos
Autores principales: Le Roch, Karine G, Johnson, Jeffrey R, Ahiboh, Hugues, Chung, Duk-Won D, Prudhomme, Jacques, Plouffe, David, Henson, Kerstin, Zhou, Yingyao, Witola, William, Yates, John R, Mamoun, Choukri Ben, Winzeler, Elizabeth A, Vial, Henri
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596145/
https://www.ncbi.nlm.nih.gov/pubmed/18973684
http://dx.doi.org/10.1186/1471-2164-9-513

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