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Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfaces
BACKGROUND: Empirical binding models have previously been investigated for the energetics of protein complexation (ΔG models) and for the influence of mutations on complexation (i.e. differences between wild-type and mutant complexes, ΔΔG models). We construct binding models to directly compare thes...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596146/ https://www.ncbi.nlm.nih.gov/pubmed/18939984 http://dx.doi.org/10.1186/1471-2105-9-448 |