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On immunosurveillance in human cancer.
The extraordinarily high incidence of cancers of many different varieties--carcinomas and lymphomas--in organ-transplant patients being maintained for long periods of time with immunosuppressive drugs is briefly reviewed. The role of immunosurveillance as a primary defense mechanism against cancer i...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Yale Journal of Biology and Medicine
1982
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596448/ https://www.ncbi.nlm.nih.gov/pubmed/6758376 |
| Sumario: | The extraordinarily high incidence of cancers of many different varieties--carcinomas and lymphomas--in organ-transplant patients being maintained for long periods of time with immunosuppressive drugs is briefly reviewed. The role of immunosurveillance as a primary defense mechanism against cancer in human beings is consistent with these observations and is in need of further investigation. Conceivably, this mechanism may play a somewhat different role in humans from what has been observed in most experimental animal models. |
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