Fever: Its History, Cause, and Function

Concepts of fever from Hippocrates to the present are briefly outlined and compared with current ideas of the pathogenesis of fever. Evidence is presented that endogenous pyrogen, the hormone that elevates body temperature, is identical with lymphocyte-activating factor, a monokine that stimulates l...

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Detalles Bibliográficos
Autor principal: Atkins, Elisha
Formato: Texto
Lenguaje:English
Publicado: 1982
Materias:
Pathogenesis and Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596465/
https://www.ncbi.nlm.nih.gov/pubmed/6758374
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author Atkins, Elisha
author_facet Atkins, Elisha
author_sort Atkins, Elisha
collection PubMed
description Concepts of fever from Hippocrates to the present are briefly outlined and compared with current ideas of the pathogenesis of fever. Evidence is presented that endogenous pyrogen, the hormone that elevates body temperature, is identical with lymphocyte-activating factor, a monokine that stimulates lymphocyte proliferation and function. It now appears that inflammation and fever are closely interrelated phenomena that are modulated by a single hormone and that have been selected by evolution to protect the host against infection.
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spelling pubmed-25964652008-12-05 Fever: Its History, Cause, and Function Atkins, Elisha Yale J Biol Med Pathogenesis and Immunology Concepts of fever from Hippocrates to the present are briefly outlined and compared with current ideas of the pathogenesis of fever. Evidence is presented that endogenous pyrogen, the hormone that elevates body temperature, is identical with lymphocyte-activating factor, a monokine that stimulates lymphocyte proliferation and function. It now appears that inflammation and fever are closely interrelated phenomena that are modulated by a single hormone and that have been selected by evolution to protect the host against infection. 1982 /pmc/articles/PMC2596465/ /pubmed/6758374 Text en
spellingShingle Pathogenesis and Immunology
Atkins, Elisha
Fever: Its History, Cause, and Function
title Fever: Its History, Cause, and Function
title_full Fever: Its History, Cause, and Function
title_fullStr Fever: Its History, Cause, and Function
title_full_unstemmed Fever: Its History, Cause, and Function
title_short Fever: Its History, Cause, and Function
title_sort fever: its history, cause, and function
topic Pathogenesis and Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596465/
https://www.ncbi.nlm.nih.gov/pubmed/6758374
work_keys_str_mv AT atkinselisha feveritshistorycauseandfunction

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