Cargando…
UPF201 Archaeal Specific Family Members Reveal Structural Similarity to RNA-Binding Proteins but Low Likelihood for RNA-Binding Function
We have determined X-ray crystal structures of four members of an archaeal specific family of proteins of unknown function (UPF0201; Pfam classification: DUF54) to advance our understanding of the genetic repertoire of archaea. Despite low pairwise amino acid sequence identities (10–40%) and the abs...
Autores principales: | Rao, Krishnamurthy N., Burley, Stephen K., Swaminathan, Subramanyam |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596488/ https://www.ncbi.nlm.nih.gov/pubmed/19079550 http://dx.doi.org/10.1371/journal.pone.0003903 |
Ejemplares similares
-
X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family
por: Tyagi, Rajiv, et al.
Publicado: (2007) -
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation
por: Bufton, Joshua C, et al.
Publicado: (2022) -
Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay
por: Hurt, Jessica A., et al.
Publicado: (2013) -
Mammalian UPF3A and UPF3B can activate nonsense‐mediated mRNA decay independently of their exon junction complex binding
por: Yi, Zhongxia, et al.
Publicado: (2022) -
Crystal Structure of the S. solfataricus Archaeal Exosome Reveals Conformational Flexibility in the RNA-Binding Ring
por: Lu, Changrui, et al.
Publicado: (2010)