Isolation of a new HIV-2 group in the US

Human immunodeficiency virus type 2 (HIV-2) emerged following cross-species transmission of simian immunodeficiency virus (SIV) from sooty mangabeys to humans several decades ago. The epidemic groups of HIV-2 have been established in the human population for at least 50 years. However, it is likely...

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Autores principales: Smith, Stephen M, Christian, Deanna, de Lame, Valéry, Shah, Urvi, Austin, Louise, Gautam, Rajeev, Gautam, Aarti, Apetrei, Cristian, Marx, Preston A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596787/
https://www.ncbi.nlm.nih.gov/pubmed/19014599
http://dx.doi.org/10.1186/1742-4690-5-103
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author Smith, Stephen M
Christian, Deanna
de Lame, Valéry
Shah, Urvi
Austin, Louise
Gautam, Rajeev
Gautam, Aarti
Apetrei, Cristian
Marx, Preston A
author_facet Smith, Stephen M
Christian, Deanna
de Lame, Valéry
Shah, Urvi
Austin, Louise
Gautam, Rajeev
Gautam, Aarti
Apetrei, Cristian
Marx, Preston A
author_sort Smith, Stephen M
collection PubMed
description Human immunodeficiency virus type 2 (HIV-2) emerged following cross-species transmission of simian immunodeficiency virus (SIV) from sooty mangabeys to humans several decades ago. The epidemic groups of HIV-2 have been established in the human population for at least 50 years. However, it is likely that new divergent SIVs can infect humans and lead to new outbreaks. We report the isolation of a new strain of HIV-2, HIV2-NWK08F, from an immunodeficient Sierra Leone immigrant. Health care providers in Sierra Leone and elsewhere need to be alerted that a subtype of HIV-2, which is not detected by PCR for epidemic HIV-2 strains, exists and can lead to immunosuppression.
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spelling pubmed-25967872008-12-06 Isolation of a new HIV-2 group in the US Smith, Stephen M Christian, Deanna de Lame, Valéry Shah, Urvi Austin, Louise Gautam, Rajeev Gautam, Aarti Apetrei, Cristian Marx, Preston A Retrovirology Correspondence Human immunodeficiency virus type 2 (HIV-2) emerged following cross-species transmission of simian immunodeficiency virus (SIV) from sooty mangabeys to humans several decades ago. The epidemic groups of HIV-2 have been established in the human population for at least 50 years. However, it is likely that new divergent SIVs can infect humans and lead to new outbreaks. We report the isolation of a new strain of HIV-2, HIV2-NWK08F, from an immunodeficient Sierra Leone immigrant. Health care providers in Sierra Leone and elsewhere need to be alerted that a subtype of HIV-2, which is not detected by PCR for epidemic HIV-2 strains, exists and can lead to immunosuppression. BioMed Central 2008-11-14 /pmc/articles/PMC2596787/ /pubmed/19014599 http://dx.doi.org/10.1186/1742-4690-5-103 Text en Copyright © 2008 Smith et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Correspondence
Smith, Stephen M
Christian, Deanna
de Lame, Valéry
Shah, Urvi
Austin, Louise
Gautam, Rajeev
Gautam, Aarti
Apetrei, Cristian
Marx, Preston A
Isolation of a new HIV-2 group in the US
title Isolation of a new HIV-2 group in the US
title_full Isolation of a new HIV-2 group in the US
title_fullStr Isolation of a new HIV-2 group in the US
title_full_unstemmed Isolation of a new HIV-2 group in the US
title_short Isolation of a new HIV-2 group in the US
title_sort isolation of a new hiv-2 group in the us
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596787/
https://www.ncbi.nlm.nih.gov/pubmed/19014599
http://dx.doi.org/10.1186/1742-4690-5-103
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