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Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance

BACKGROUND: Anthracyclines and taxanes are commonly used in the treatment of breast cancer. However, tumor resistance to these drugs often develops, possibly due to overexpression of drug transporters. It remains unclear whether drug resistance in vitro occurs at clinically relevant doses of chemoth...

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Detalles Bibliográficos
Autores principales:	Hembruff, Stacey L, Laberge, Monique L, Villeneuve, David J, Guo, Baoqing, Veitch, Zachary, Cecchetto, Melanie, Parissenti, Amadeo M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596802/ https://www.ncbi.nlm.nih.gov/pubmed/18980695 http://dx.doi.org/10.1186/1471-2407-8-318

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