Modulation of Macrophage Activation State Protects Tissue from Necrosis during Critical Limb Ischemia in Thrombospondin-1-Deficient Mice

BACKGROUND: Macrophages, key regulators of healing/regeneration processes, strongly infiltrate ischemic tissues from patients suffering from critical limb ischemia (CLI). However pro-inflammatory markers correlate with disease progression and risk of amputation, suggesting that modulating macrophage...

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Detalles Bibliográficos
Autores principales: Bréchot, Nicolas, Gomez, Elisa, Bignon, Marine, Khallou-Laschet, Jamila, Dussiot, Michael, Cazes, Aurélie, Alanio-Bréchot, Cécile, Durand, Mélanie, Philippe, Josette, Silvestre, Jean-Sébastien, Van Rooijen, Nico, Corvol, Pierre, Nicoletti, Antonino, Chazaud, Bénédicte, Germain, Stéphane
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597179/
https://www.ncbi.nlm.nih.gov/pubmed/19079608
http://dx.doi.org/10.1371/journal.pone.0003950

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