Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs

The peptidic anti-HIV drug T20 (Fuzeon) and its analog C34 share a common heptad repeat (HR) sequence, but they have different functional domains, i.e., pocket- and lipid-binding domains (PBD and LBD, respectively). We hypothesize that novel anti-HIV peptides may be designed by using artificial sequ...

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Detalles Bibliográficos
Autores principales: Shi, Weiguo, Qi, Zhi, Pan, Chungen, Xue, Na, Debnath, Asim K., Qie, Jiankun, Jiang, Shibo, Liu, Keliang
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597519/
https://www.ncbi.nlm.nih.gov/pubmed/18682248
http://dx.doi.org/10.1016/j.bbrc.2008.07.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597519/
https://www.ncbi.nlm.nih.gov/pubmed/18682248
http://dx.doi.org/10.1016/j.bbrc.2008.07.134

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