Cargando…
Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs
The peptidic anti-HIV drug T20 (Fuzeon) and its analog C34 share a common heptad repeat (HR) sequence, but they have different functional domains, i.e., pocket- and lipid-binding domains (PBD and LBD, respectively). We hypothesize that novel anti-HIV peptides may be designed by using artificial sequ...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597519/ https://www.ncbi.nlm.nih.gov/pubmed/18682248 http://dx.doi.org/10.1016/j.bbrc.2008.07.134 |