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Reduced Basal ATP Synthetic Flux of Skeletal Muscle in Patients with Previous Acromegaly

BACKGROUND: Impaired mitochondrial function and ectopic lipid deposition in skeletal muscle and liver have been linked to decreased insulin sensitivity. As growth hormone (GH) excess can reduce insulin sensitivity, we examined the impact of previous acromegaly (AM) on glucose metabolism, lipid stora...

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Detalles Bibliográficos
Autores principales: Szendroedi, Julia, Zwettler, Elisabeth, Schmid, Albrecht Ingo, Chmelik, Marek, Pacini, Giovanni, Kacerovsky, Gertrud, Smekal, Gerhard, Nowotny, Peter, Wagner, Oswald, Schnack, Christoph, Schernthaner, Guntram, Klaushofer, Klaus, Roden, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599885/
https://www.ncbi.nlm.nih.gov/pubmed/19093000
http://dx.doi.org/10.1371/journal.pone.0003958