Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strength...

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Detalles Bibliográficos
Autores principales: Durand, Rémy, Prendki, Virginie, Cailhol, Johann, Hubert, Véronique, Ralaimazava, Pascal, Massias, Laurent, Bouchaud, Olivier, Le Bras, Jacques
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600204/
https://www.ncbi.nlm.nih.gov/pubmed/18258131
http://dx.doi.org/10.3201/eid1402.070945
Descripción
Sumario:We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.

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