Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strength...

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Detalles Bibliográficos
Autores principales: Durand, Rémy, Prendki, Virginie, Cailhol, Johann, Hubert, Véronique, Ralaimazava, Pascal, Massias, Laurent, Bouchaud, Olivier, Le Bras, Jacques
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600204/
https://www.ncbi.nlm.nih.gov/pubmed/18258131
http://dx.doi.org/10.3201/eid1402.070945
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author Durand, Rémy
Prendki, Virginie
Cailhol, Johann
Hubert, Véronique
Ralaimazava, Pascal
Massias, Laurent
Bouchaud, Olivier
Le Bras, Jacques
author_facet Durand, Rémy
Prendki, Virginie
Cailhol, Johann
Hubert, Véronique
Ralaimazava, Pascal
Massias, Laurent
Bouchaud, Olivier
Le Bras, Jacques
author_sort Durand, Rémy
collection PubMed
description We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.
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spelling pubmed-26002042009-01-13 Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure Durand, Rémy Prendki, Virginie Cailhol, Johann Hubert, Véronique Ralaimazava, Pascal Massias, Laurent Bouchaud, Olivier Le Bras, Jacques Emerg Infect Dis Dispatch We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened. Centers for Disease Control and Prevention 2008-02 /pmc/articles/PMC2600204/ /pubmed/18258131 http://dx.doi.org/10.3201/eid1402.070945 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Durand, Rémy
Prendki, Virginie
Cailhol, Johann
Hubert, Véronique
Ralaimazava, Pascal
Massias, Laurent
Bouchaud, Olivier
Le Bras, Jacques
Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_full Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_fullStr Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_full_unstemmed Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_short Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_sort plasmodium falciparum malaria and atovaquone-proguanil treatment failure
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600204/
https://www.ncbi.nlm.nih.gov/pubmed/18258131
http://dx.doi.org/10.3201/eid1402.070945
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