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Macrolide-Resistant Shigella sonnei

Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit...

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Autores principales: Boumghar-Bourtchai, Leyla, Mariani-Kurkdjian, Patricia, Bingen, Edouard, Filliol, Ingrid, Dhalluin, Anne, Ifrane, Shadia Ait, Weill, François-Xavier, Leclercq, Roland
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600399/
https://www.ncbi.nlm.nih.gov/pubmed/18680661
http://dx.doi.org/10.3201/eid1408.080147
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author Boumghar-Bourtchai, Leyla
Mariani-Kurkdjian, Patricia
Bingen, Edouard
Filliol, Ingrid
Dhalluin, Anne
Ifrane, Shadia Ait
Weill, François-Xavier
Leclercq, Roland
author_facet Boumghar-Bourtchai, Leyla
Mariani-Kurkdjian, Patricia
Bingen, Edouard
Filliol, Ingrid
Dhalluin, Anne
Ifrane, Shadia Ait
Weill, François-Xavier
Leclercq, Roland
author_sort Boumghar-Bourtchai, Leyla
collection PubMed
description Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.
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spelling pubmed-26003992009-01-13 Macrolide-Resistant Shigella sonnei Boumghar-Bourtchai, Leyla Mariani-Kurkdjian, Patricia Bingen, Edouard Filliol, Ingrid Dhalluin, Anne Ifrane, Shadia Ait Weill, François-Xavier Leclercq, Roland Emerg Infect Dis Dispatch Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis. Centers for Disease Control and Prevention 2008-08 /pmc/articles/PMC2600399/ /pubmed/18680661 http://dx.doi.org/10.3201/eid1408.080147 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Boumghar-Bourtchai, Leyla
Mariani-Kurkdjian, Patricia
Bingen, Edouard
Filliol, Ingrid
Dhalluin, Anne
Ifrane, Shadia Ait
Weill, François-Xavier
Leclercq, Roland
Macrolide-Resistant Shigella sonnei
title Macrolide-Resistant Shigella sonnei
title_full Macrolide-Resistant Shigella sonnei
title_fullStr Macrolide-Resistant Shigella sonnei
title_full_unstemmed Macrolide-Resistant Shigella sonnei
title_short Macrolide-Resistant Shigella sonnei
title_sort macrolide-resistant shigella sonnei
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600399/
https://www.ncbi.nlm.nih.gov/pubmed/18680661
http://dx.doi.org/10.3201/eid1408.080147
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